Kathryn Hamilton, PhD & Amanda Muir, MD, MTR

Join us for a seminar by Drs. Kathryn Hamilton and Amanda Muir, Associate Professors of Pediatrics.

Title: Leveraging patient-derived organoids for understanding gastrointestinal diseases

Location: KRB 253

Time: 3:oopm-4:00pm

Abstract

Drs. Kathryn Hamilton and Amanda Muir co-founded the CHOP GI Epithelium Modeling (GEM) Program in 2019 to advance patient-derived intestinal organoid systems for studying human biology in health and disease. The GEM Program, through its Core launched in 2024, provides shared infrastructure, standardized protocols, and biobanked tissue that enable investigators across CHOP and Penn to model gastrointestinal tissue responses to genetic, microbial, and environmental insults with human-relevant precision. As the program scales into a broader resource, it offers strong potential for partnership with environmental toxicology researchers seeking to apply organoid-based models toward understanding how environmental exposures impact cell function and disease risk.